ANTI-INFLAMMATORY ACTIVITY OF COPPER NANOPARTICLES SYNTHESIZED USING DRIED GINGER | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

 Inflammation is an immune system biochemical response that can be activated by a wide range of factors, including bacteria, damaged cells, and toxic compounds. The Zingiberaceae family includes ginger (Zingiber officinale). Ginger's phytochemistry is responsible for its health-promoting properties. Ginger is also said to have anti-inflammatory and antioxidative properties that help to slow down the ageing process. It also has antimicrobial properties that can help in infectious disease treatment. Oxidative stress occurs when free radicals or reactive oxygen species (ROS) are generated in excess of the biological system's antioxidant capacity throughout metabolism. The aim of this study is to see how effective copper nanoparticles are at reducing inflammation when they are combined with dried ginger. The Zingiber officinale was harvested, peeled, washed, and air dried in a shady spot, after which a plant extract was produced and copper nanoparticles were made. The synthesis of copper nanoparticles was monitored using a UV-Vis spectrophotometer on a regular basis. The inhibition of albumin denaturation assay test was used to assess anti-inflammatory activity, and the results revealed that dried ginger mediated copper nanoparticles had potent anti-inflammatory properties.

Please see the link:- https://www.ikprress.org/index.php/PCBMB/article/view/5602

CYTOTOXICITY OF COPPER NANOPARTICLES SYNTHESIZED USING DRIED GINGER | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

 Copper nanoparticles are used in a wide range of fields, including medicine, agriculture, and engineering, to name a few. This biotechnology incorporates biological concepts of physical and chemical properties to create nano-sized particles with unusual properties. The quality of being harmful to cells is known as cytotoxicity. The goal of this study was to look at the cytotoxicity of copper nanoparticles made from dried ginger. Copper nanoparticles were synthesised using a green method and characterised using UV-VIS spectroscopy. The brine shrimp lethality assay was used to assess the cytotoxicity of the dried ginger induced copper nanoparticles at various concentrations. The findings showed that copper nanoparticles made from dried ginger had lower toxicity when used at lower concentrations. As a result, different nano-formulations of dried ginger mediated copper nanoparticles can be produced at optimal concentrations for safe and cost-effective therapeutics.

Please see the link:- https://www.ikprress.org/index.php/PCBMB/article/view/5584