EVALUATION OF HYPOGLYCEMIC POTENTIAL OF AQUEOUS BARK EXTRACT OF Pterocarpus marsupium- AN in vitro STUDY | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

 Diabetes is a chronic disorder associated with the interruption of carbohydrates, fats and protein metabolism characterised by increased fasting and postprandial blood sugar levels. The traditional anti diabetic remedies using plants with hypoglycemic activity is always safe due to their holistic approach and low cost. Pterocarpus marsupium belongs to the family fabaceae and commonly known as “INDIAN KINO TREE”, they are used in various ailments in folk medicine. The aim of this study is to evaluate the hypoglycemic activity of aqueous extract of Pterocarpus marsupium. This plant also finds its use as a cardiotonic and hepatoprotective agent. The herbal extract was prepared by using the herbal powder and it was tested for the hypoglycemic activity by alpha amylase inhibitory activity and alpha glucosidase inhibitory activity. The datas were collected and statistically analysed. From the results it is evidence that the aqueous bark extract of Pterocarpus marsupium possesses hypoglycemic potential. The synthetic drug currently used for diabetes only decreases the symptoms and on the long run can have side effects too. Herbal medicine if formulated can act as a good shield. Since chronic diabetes leads to excessive and uncontrolled degeneration, it is always better to treat diabetes with herbal formulations instead of synthetic drugs.

Diabetes is a chronic disorder associated with the interruption of carbohydrates, fats and protein metabolism characterised by increased fasting and postprandial blood sugar levels. The traditional anti diabetic remedies using plants with hypoglycemic activity is always safe due to their holistic approach and low cost. Pterocarpus marsupium belongs to the family fabaceae and commonly known as “INDIAN KINO TREE”, they are used in various ailments in folk medicine. The aim of this study is to evaluate the hypoglycemic activity of aqueous extract of Pterocarpus marsupium. This plant also finds its use as a cardiotonic and hepatoprotective agent. The herbal extract was prepared by using the herbal powder and it was tested for the hypoglycemic activity by alpha amylase inhibitory activity and alpha glucosidase inhibitory activity. The datas were collected and statistically analysed. From the results it is evidence that the aqueous bark extract of Pterocarpus marsupium possesses hypoglycemic potential. The synthetic drug currently used for diabetes only decreases the symptoms and on the long run can have side effects too. Herbal medicine if formulated can act as a good shield. Since chronic diabetes leads to excessive and uncontrolled degeneration, it is always better to treat diabetes with herbal formulations instead of synthetic drugs.

Please see the link :- https://www.ikprress.org/index.php/PCBMB/article/view/5307

AN UPDATE REVIEW OF MOROCCAN MEDICINAL PLANTS USED TO TREAT DIABETES | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

 Traditional plants are used in Morocco to treat different diseases including diabetes mellitus.Diabetes is a serious health problem and a major cause of mortality.The purpose of this review consist to report all herbal medicines, their part used, the traditional uses, and the frequency of citation based on ethnobotanical studies finding in different regions of Morocco.Several databases including PubMed, Springer, Science Direct, Scopus, Google Scholar, Hindawi, and Taylor & Francis are used to determine ethnobotanical medicinal plants used against diabetes.Results revealed the identification of 206 plants from 64 families belonging to several botanical families including Lamiaceae, Fabaceae, Asteraceae, Apiaceae.Trigonella foenum-graecum, Olea europaea, Artemisia herba-alba, Citrullus colocynthis, Nerium oleander and Salvia officinalishave been reported with a highest percentage of frequency occurrence. Some of these plants presented an efficient in vitro andin vivohypoglycemic effect. Indeed, the antidiabetic mechanism of action is not full understood. However, the antidiabetic activities of luteolin, oleuropein, chlorogenic acid, and apigeninisolatedare nowstudied. These compounds induce the antidiabetic effect viathe inhibition of the PKB/AKT pathway, and PPARγ expression and the activation of AMPK and PI3K-GSK3 pathways. These molecules present a potential as an alternative compounds in diabetes therapeutic strategy and further studies should be performed to elaborate their effects in clinical trials.

Please see the link :- https://www.ikprress.org/index.php/PCBMB/article/view/5279

CHEMISTRY OF TURMERIC: A GOLDEN SPICE WITH THE MULTIFUNCTIONAL BENEFITS | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

 Turmeric is generally known for its use as spice in cooking. It is often considered as the king of spices.  Its use in the customary arrangement of medication for a considerable length of time and has been experimentally approved broadly. Through this review, researchers try to bring to notice the beneficial use of this naturally gifted spice called turmeric. Turmeric has always received considerable interest among the researchers/scientific community because of its medical and cosmetic properties. It is beyond doubt or debate that turmeric is being used for various reasons. Extensive researches time and again has proved that it has potential to treat many diseases. Curcumin a main ingredient of turmeric is the most effective in treatment. It is also beneficial and useful for skin treatment. It has different valuable properties such as antioxidant exercises and is helpful in conditions, for example, cancers, inflammation, etc. It likewise has antifungal, antimicrobial renal and hepatoprotective exercises. In this way, it has the potential against different cancer growth, diabetes, sensitivities, joint inflammation and other incessant and hard treatable infections. Both conventional and improved method of technology is used for producing turmeric and due to its multi benefits, day by day turmeric is occupying a major share in the world market specially with the entrance of latest technology and government support for small and medium scale industries.

Please see the link :- https://www.ikprress.org/index.php/PCBMB/article/view/5212