Aim: To estimate the antioxidant and cytotoxicity activity of selenium nanoparticles-mediated Solanum trilobatum.
Introduction:
One of the most essential medicinal plants emerging in the southern regions of
India is Solanum trilobatum, commonly called thuthuvalai. It is traditionally
used in the treatment of different ailments. Certain illnesses such as
tuberculosis, respiratory disorders and bronchial asthma are said to be healed.
Phytochemical analysis of different extracts, such as chloroform, S. water. The
existence of secondary metabolites such as steroids, triterpenoids,
carbohydrates, sugar reducers and phenolic compounds was demonstrated by
trilobatum. S. Antimicrobial activity, cytotoxicity activity, protective
effect, haemolytic activity are said to be possessed by trilobatum.
Materials and Methods: The plant extract was prepared and the UV-Beckmann
spectrometer was used to synthesise nanoparticles. The nanoparticles that were
synthesised were then centrifuged. Following centrifugation, pellet collection
was completed. This has been used to test various properties, such as
antioxidants and cytotoxicity. The antioxidant property was tested as a normal
solution using a DPPH assay where ascorbic acid was used. Wells were used for
the cytotoxicity operation, where the mortality rate of the shrimps was
calculated when selenium nanoparticle-mediated plant extracts of different
concentrations were applied.
Results: In the case of cytotoxicity activity, solanum trilobatum induced by
selenium nanoparticles showed elevated LD 50 in higher concentrations. In
comparison with regular ascorbic acid, the plant extract mediated selenium
nanoparticle had a major impact on antioxidant function.
Please see the link :- https://www.ikprress.org/index.php/PCBMB/article/view/5312
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