Goal: The aim of the present study is to assess the anti-inflammatory and anti-microbial activity of selenium nanoparticles mediated by Solanum trilobatum.
Materials and Methods: 1g of Solanum trilobatum powder with 0.519 g of sodium selenite with 50 ml of distilled water was used to prepare the plant extract. They then collected the extract and held it in a laboratory shaker for a few hours to synthesise selenium nanoparticles. The colour shift was detected every two hours and the readings were taken using a UV spectrometer.Results and Discussion: Selenium nanoparticles showed a higher percentage of protein denaturation inhibition at 50 μL due to the anti-inflammatory impact. If the concentration increases, the inhibition percentage simultaneously increases. Effective inhibition against Streptococcus mutans, Lactobacillus sp and Candida albicans was shown by the anti-microbial activity of Solanum trilobatum mediated selenium nanoparticles. In our research, antimicrobial activity showed a higher-than-standard inhibition zone against S. Lactobacillus and mutans. In our research, antifungal activity showed an inhibition zone against Candida albicans almost identical to the norm used.
Conclusion: Due to the altered and outstanding properties of nanoscale materials, nanoscience and nanotechnology have numerous promising applications. The current study has shown that SeNPs controlled by Solanum trilobatum have excellent anti-inflammatory and antimicrobial activity. So this present study will provide understanding and pave a way for new medicines to be developed that could replace the norm in the future.
Please see the link :- https://www.ikprress.org/index.php/PCBMB/article/view/5311
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