Wednesday, January 20, 2021

ANTIMICROBIAL ACTIVITY OF CLOVE AND CINNAMON FORMULATION MEDIATED SELENIUM NANOPARTICLES AGAINST ORAL PATHOGENS | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

Background: A large range of fields, including medicine in particular, have been modernised by the advent of nanoparticles (NPs). By minimising the toxicity and side effects that commercially available drugs may have on patients, nanoparticles have revolutionised targeted drug delivery. In herbal medicine, cloves and cinnamon have long been used for the treatment of a broad range of ailments and diseases. The green synthesis of nanoparticles has been gaining importance because of its simplicity and eco-friendliness.

Goal: The aim of this study was to synthesise selenium nanoparticles mediated by clove and cinnamon formulations and evaluate their antimicrobial activity against oral pathogens.

Materials and Methods: Selenium nanoparticles mediated by clove and cinnamon formulations were synthesised in vitro. The antimicrobial activity of SeNPs was tested using the Kirby Bauer disc diffusion method against Streptococcus mutans and Lactobacillus.

Results: SeNPs mediated by clove-cinnamon extract showed effective antimicrobial activity comparable to that of drugs commercially available.

Conclusion: It can thus be inferred that selenium nanoparticles mediated by clove-cinnamon have the potential to be used as an effective antibiotic. To isolate the component in the extract that makes it effective to be used in large-scale production for targeted drug delivery against a wide range of oral microbial infections, this formulation needs to be further purified.

Please see the link :-
https://www.ikprress.org/index.php/PCBMB/article/view/5350

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