Cordia dichotoma is the target. G. Forst is a member of the Boraginaceae family, which is known for its biological activities. Ulcers have been treated with powdered plant stem bark. Antimicrobial and anti-implantation properties are found in the stem bark. The aim of this study is to use GC-MS to determine the phytoconstituents of stem bark hexane extract and to investigate its antibacterial activity. Methods: Cold and hot hexane solvents were used to remove the powdered stem bark, and the solvent was then distilled to determine its constituents using GCMS. Saponification, column chromatography, and preparative TLC were used to purify the crude hexane. GCMS was used to evaluate the fractions obtained from the above-mentioned methods. The disc diffusion method was used to test the hexane extract for antibacterial activity against two bacterial pathogens. Based on peak area percentage, retention time, and structure, eleven components from crude hexane extract, eight components from Fraction 16c, and three components from Fraction 16d were classified using GCMS.
Please see the link - https://www.ikprress.org/index.php/PCBMB/article/view/5666
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