When left unsupervised, Streptococcus mutans (Sm), the harbinger of dental decay, is a pathogenic bacterium that has been linked to the pathogenesis of cardiovascular diseases. With the right inhibitory measures in place, we can reduce its role in exacerbating morbidity. The goal of our research was to look into the antibacterial potential of selenium nanoparticles (Se-NPs) made from Symplocos racemosa (Sr).
Sr was pulverised and turned into a filtered herbal formulation. For the synthesis of nanoparticles, sodium selenite solution was added to it, and the mixture was kept in a magnetic stirrer. UV-vis spectroscopy was used to characterise the Se-NPs, which were then centrifuged until the final pellet was obtained. On a Muller-Hinton Agar plate, a fresh bacterial suspension of Sm was scattered. The plate was incubated at 37°C for 24 hours with Se-NP concentrations of (50, 100, and 150) l in each well. The zones of inhibition were measured using antibiotics as a control.
Following the synthesis of Se-NPs, there was a visible colour change. UV-vis spectroscopy was used to characterise the prepared particles, and a peak at 280 nm was discovered. With an increase in Se-NP concentration, the inhibition zones grew larger. The antibacterial control was followed by 150 L of our Se-NPs, which was the most effective against Sm.
Conclusion: Sr-derived Se-NPs are effective antibacterial agents against Sm. They're non-toxic, quick, and simple to make, and they could be an inexpensive way to control Sm.
Please see the link :- https://www.ikprress.org/index.php/PCBMB/article/view/5557
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