Saturday, March 20, 2021

ANTIBACTERIAL ACTIVITY OF Phyllanthus emblica & Cinnamomum verum FORMULATION MEDIATED SILVER NANOPARTICLES AGAINST ORAL PATHOGENS | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

 Silver nanoparticles (AgNPS) are a form of nanoparticle that has antibacterial properties and is toxic to disease-causing bacteria. This is due to the influence of surface enhancement, which causes nanocrystalline materials to become more reactive. Antimicrobial properties increase by more than 99 percent when particles are in the nanometer range, which has been linked to form, scale, and functional groups in nanoparticles. Due to its low cost and environmental compatibility, as well as the absence of toxins and harmful substances, green synthesis of silver nanoparticles using herbal products has gotten a lot of publicity.

The aim was to test the antibacterial activity of silver nanoparticles made from Phyllanthus emblica and Cinnamomum verum fruit formulations against oral pathogens.

Conical flask, distilled water, filter paper, fruit extract powder, and petri-disks were used in this experiment.

Our findings revealed strong antibacterial activity against oral pathogens. The diameter of the zone of inhibition found during antibacterial activity evaluation suggests that staphylococcus aureus has the most activity, followed by Lactobacillus, Enterococcus faecalis, and Streptococcus mutans. AgNPS may bind to the cell membrane's surface, disrupting permeability and respiration association functions. Morenos et al. speculate that AgNPS may enter bacteria cells and cause damage by interacting with DNA.

Conclusion: Our results indicate that AgNPS derived from Phyllanthus emblica and Cinnamomum verum have antibacterial activity against oral pathogens. As a result, by mixing it into toothpaste and mouthwash, it can be used as an important therapeutic agent against a variety of oral diseases.

Please see the link :-
https://www.ikprress.org/index.php/PCBMB/article/view/5548

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