Friday, February 5, 2021

EVALUATION OF ANTIMICROBIAL PROPERTY OF HERBAL MOUTHWASH USING CRANBERRY EXTRACT: A PILOT STUDY | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

Background: Dental plaque-induced oral diseases continue to affect the majority of the world's population. Among them, the single most common and preventable oral infectious disease is dental caries. As fresh fruit, juice, and even as medicine, cranberry is used. It has activities that are antimicrobial, anti inflammatory, and anti-tumor. In various systemic infections, it is also known to cause bacterial adhesion. It is less popular for its dental application, however. There is, therefore, a need to determine its effect on oral infections.

Aim: The objective of the study was to test the antimicrobial property of herbal mouthwash using cranberry extract.

Materials and Methods: This unique research was performed at Saveetha Dental College and Hospitals, Chennai, as a single blinded, parallel group clinical trial. It consisted of a total of 10 subjects randomly divided into groups with a fair gingival index (aged 18-22 years) and given 5 ml of chlorhexidine mouthwash and cranberry mouthwash twice daily to Group A (n=5) and Group B (n=5) for 7 days each. At baseline, plaque samples were obtained and the microbial count was measured after 7 days of using mouthwash.

Results and Discussion: This research indicates that the microbial count has decreased substantially before and after the use of cranberry mouthwash and chlorhexidine mouthwash. There was a statistically significant difference (p<0.05) between the baseline mean amount of CFU/ml and the chlorhexidine and cranberry groups after 7 days. For the cranberry group, the mean reduction was 52 percent, while the mean reduction after use was 53 percent in the chlorhexidine group.

Conclusion: This analysis revealed that there was a substantial decrease in the microbial count in both classes. Therefore, in order to improve oral health, herbal products such as cranberry have been shown to be more effective or similar alternatives to chlorhexidine, with added benefits and minimal side effects.

Please see the link :-
https://www.ikprress.org/index.php/PCBMB/article/view/5529

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