Aim: The research aims to evaluate the copper nanoparticles mediated by Celastrus paniculatus and their antimicrobial and antioxidant function.
Presentation: C. A member of the family Celastraceae, paniculatus is a large, woody climber with a corky yellow bark. It is found throughout India and has been recorded to grow to almost 2000 m in height. There are varying degrees of therapeutic values in plants, some of which are used to treat cognitive dysfunction, epilepsy, insomnia, rheumatism, gout, dyspepsia. The most widely used plant portion is oil from seeds called Jyothismati oil, which contains the alkaloids celastrine and paniculatin in various quantities.Materials And Methods: To assess the antibacterial activity of copper nanoparticles, the agar well diffusion process was used. Streptococcus mutans, Candida albicans and Lactobacillus spp. were screened against different concentrations of CuNPs. As a positive monitor, antibiotics were used. Inhibition zones were reported on each plate. In 5 test tubes ranging from 10 to 50 microliters and held in a dark place for 10 minutes, 50 percent methanol, DPPH solution and CuNP were added for antioxidant activity and the reading was noted.
Results: As a consequence, a dose-dependent incremental increase in activity of S is observed. C. Mutans. Lactobacillus spp., Albicans. As compared to the normal and antioxidant activity, 150 microliters were observed in 50 microliters where the percentage of inhibition was maximum.
Conclusion: As a consequence of this, it is inferred that C. Copper nanoparticles mediated by paniculates have a strong antimicrobial and antifungal activity, and it also has a good antioxidant impact.
Please see the link :- https://www.ikprress.org/index.php/PCBMB/article/view/5336
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