ANTIBACTERIAL ACTIVITY OF CINNAMON - CLOVE MEDIATED SILVER NANOPARTICLES AGAINST Streptococcus mutans | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

Context: There are protective properties of cinnamon and clove against oral pathogens. Streptococcus mutans is responsible for the creation of cavities. Synthetic drugs were used to the full and the scientific area in terms of medicine was taken over by newer nanoparticles. As they appear to have little or no side effect on human health, herbal extracts contained abundantly need to be used more.

Aim: This research was conducted to test the antibacterial efficacy against Streptococcus mutans of Cinnamon-Clove mediated Silver nanoparticles.

Materials and Methods: We procured herbal powders. After maximum activity was noted by UV spectroscopy, an aqueous extract was prepared and centrifugated. The inoculated culture plates were added to different volumes of the Silver nanoparticles containing Cinnamon and Clove combinations. The inhibition zones were measured using the technique of disc diffusion.

Results: Cinnamon-Clove mediated Silver nanoparticles had the highest amount of good antibacterial activity (10 mm inhibition zone) and this property was greater than that of widely used antibiotics (Amoxicillin-8 mm).

Conclusion: Cinnamon and Clove mediated Silver nanoparticles were examined and good antibacterial efficacy was indicated by their wider inhibition zones and this property was shown to be similar to an antibiotic. This new formulation for use against oral pathogens such as Streptococcus mutans, which is positively correlated with dental caries and periodontal disorders, can be integrated into mouthwashes and probiotic lozenges.

Please see the link :- https://www.ikprress.org/index.php/PCBMB/article/view/5348