Abstracts
Background: Periodontitis and gingivitis are the inflammatory disease in oral cavity and it’s a challenging task for a dentist to complete and safe treatment.
Aim: The study was aimed to know the antibacterial effect of chloroform, ethanol and aqueous extract of Drosera peltata J.E.Sm against clinically isolated human periodontal pathogens such as Prevotella intermedia, Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans.
Materials and Methods: Agar well diffusion assay, Minimum inhibitory concentration (MIC) assay and Minimum bactericidal concentration (MBC) were performed to assess its antibacterial potency. Amoxicillin/clavulanic acid and Tetracycline were used as standard antibiotic.
Results: Zone of inhibition was measured from agar well diffusion, where all the extracts showed bacterial growth inhibition in a concentration dependent manner whereas chloroform extracts showed the maximum inhibition at 16 µg/ml. MIC was determined by broth dilution in which chloroform extract also showed MIC (1.25 µg/ml) on A. actinomycetemcomitans and P. gingivalis. In MBC, similar to standard drug no colonies were found in chloroform extract. The orders of antibacterial effects were CEDP˃ EEDP˃ AEDP.
Conclusion: The positive results suggested that the Drosera peltata should be used as an antibacterial drug to periodontal therapy.
Keywords : Drosera peltata; antibacterial; amoxicillin/clavulanic acid; tetracycline; Minimum Inhibitory Concentration (MIC).
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