Thursday, April 1, 2021

Symplocos racemosa BARK MEDIATED COPPER NANOPARTICLES AND ITS ASSESSMENT OF ANTI-INFLAMMATORY ACTIVITY | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

 To make copper nanoparticles out of Lodhra bark and test their anti-inflammatory properties. Copper nanoparticles are antifungal and antibacterial agents that are extremely tiny. The copper free radicals then oxidise lipids in cell membranes, causing the membranes to degenerate. As a consequence of the degraded membranes, intracellular compounds leak out of cells, resulting in cell death. The local reaction of living mammalian tissues to injury is inflammation. It's a natural defence mechanism designed to stop or slow the spread of harmful agents. 1 g of freshly collected Lodhra bark is extracted and thoroughly mixed with 100 ml of distilled water, then boiled for 3 to 5 minutes in a heating mantle, filtered through filter paper, and held in a shaker. For nanoparticle synthesis, copper sulphate was combined with plant extract and kept in a shaker. Albumin denaturation assay was used to assess the anti-inflammatory function. The formation of copper nanoparticles mediated by lodhra bark was visually observed and conformed using UV visible spectroscopy. Copper nanoparticles at different concentrations have demonstrated dose-dependent inflammatory activity. In contrast to the regular 90 percent, a 50 micro lite inhibition shower has a maximum inhabitation of 81 percent. Copper nanoparticles mediated by Lodhra bark were found to be cost-effective and simple to make, with excellent anti-inflammatory properties. As a result, it will be useful in a variety of medical fields in the future.


Please see the link:- https://www.ikprress.org/index.php/PCBMB/article/view/5610

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