ANTI INFLAMMATORY ACTIVITY OF CORIANDER OLEORESIN MEDIATED SELENIUM NANOPARTICLES | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

The aim of this study was to assess the anti-inflammatory activity of selenium nanoparticles mediated by Coriander Oleoresin.

Materials and Methods: Coriander oleoresin-mediated Selenium nanoparticles were made by combining 0.5 mL Coriander Oleoresin extract with 0.519 g sodium selenite in 99.5 mL distilled water. For nanoparticle synthesis, the reaction mixture was held in an orbital shaker with magnetic stirrer. Color shift indicated the formation of selenium nanoparticles, which was confirmed using a UV-Visible spectrophotometer. The antiinflammatory activity of coriander oleoresin mediated selenium nanoparticles was assessed using an albumin denaturation inhibitory assay.

Discussion and Conclusions: The presence of selenium nanoparticles was demonstrated by a colour shift in the reaction mixture, which was verified by UV-Visible spectroscopy with a peak at 320nm. The anti-inflammatory activity of coriander oleoresin mediated selenium nanoparticles was dose dependent. At 50 L of selenium nanoparticles, the maximum inhibitory effect of 90 percent on protein denaturation was observed.

Conclusion: The synthesis of selenium nanoparticles in a green manner was simple and straightforward. The researchers concluded that Coriander Oleoresin-mediated Selenium nanoparticles had strong anti-inflammatory activity and thus could be used for a healthy and environmentally friendly selenium nanoparticle synthesis for inflammatory conditions.

Please see the link :- https://www.ikprress.org/index.php/PCBMB/article/view/5543