Saturday, January 23, 2021

ENAMEL RE-MINERALIZING CAPACITY OF GRAPE SEED EXTRACT (GSE)- A SYSTEMATIC REVIEW | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

Introduction: Dental caries are infectious diseases caused by enamel, dentin and cement dissolution caused by acidogenic bacteria. If an appropriate treatment plan for initial carious lesions is formulated, they are able to avoid hardening and then return to their healthy state. Over the years, various commercially available re-mineralizing agents have been used. A variety of plant extracts have been studied recently. Some of the plant products extensively researched are grape seed, cranberry, and guava leaves. Grape seed extract is obtained primarily from grape seeds. It is abundant in antioxidants and complexes of oligomeric proanthocyanin and has been associated with a wide range of potential health benefits.

Objective: To classify the different studies and literature in which grape seed extract was used as a re-mineralizing agent by means of systematic analysis.

Materials and Methods: Search terms such as enamel re-mineralization, enamel re-mineralizing agents, grape seed extract, de-mineralized enamel etc. were used in the electronic database (i.e. PUBMED CENTRAL and Medline) alone and in combination by means of a PUBMED search builder. In vivo or ex vivo experiments were included in the inclusion criteria in which the Grape Seed Extract (GSE) re-mineralizing ability was compared with other re-mineralizing agents.

Results: All inclusion requirements were met by a total of 3 publications. All of the included studies showed that Grape Seed Extract (GSE) had substantial or positive enamel re-mineralization potential. However, one study found that, compared to other commercially available re-mineralizing agents, the re-mineralizing ability was inferior (Standard Stannous Fluoride).

Conclusion: The study ends with the evidence available that Grape Seed Extract (GSE) is an important enamel re-mineralizing agent. However, compared to other commercially available re-mineralizing agents, its capacity to re-mineralize enamel is inferior.

Please see the link :-
https://www.ikprress.org/index.php/PCBMB/article/view/5397

No comments:

Post a Comment