Background: Inflammation is the key finding in any periodontal problem. It is important to devise new topical agents to reduce the inflammation. Zinc oxide nanoparticle synthesized from plant extract will be an eco-friendly, simple and reliable method offering therapeutic options which are safe, free of side effects and effective for a wide range of diseases. In our study we have chosen grape seed due to its protection against oxidative damage, and anti-diabetic, anti-cholesterol and antiplatelet properties.
Aim: The aim
of the present study was to analyze the anti-inflammatory activity of zinc
oxide nanoparticles synthesized using grape seed extract.
Materials and
Methods: Collection of grape seeds and preparing its extract followed by the
synthesis of zinc nanoparticles using the prepared herbal formulation. The
stable zinc nanoparticles were characterized by UV- Vis spectroscopy, which
showed shift peak at 660 nm. The anti-inflammatory activity of zinc
nanoparticles prepared using plant extract was investigated by albumin
denaturation assay. The results of the test were described as the standard
deviation (SD) and analyzed using the UV- Vis Spectroscopy.
Results: The
zinc oxide nanoparticles synthesized using the grape seed extract showed
highest absorbance at a concentration of 50 μl (84.6%) when subjected to
inhibition of albumin denaturation assay to check for its anti-inflammatory
activity.
Please see the link :- https://www.ikprress.org/index.php/PCBMB/article/view/5364
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