EFFICACY OF POMEGRANATE MOUTHWASH AS AN ANTIMICROBIAL AGENT | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

 Background: The most common oral diseases are periodontitis and tooth decay. Pomegranate mouthwash has been used in an attempt against the same with the latest controversy in herbal medicine. The purpose of the analysis was to determine the effectiveness of pomegranate mouthwash as an antimicrobial agent.

Content and Methods: As per a previous study, the mouthwash was prepared using pomegranate seeds. This double-blinded research was conducted on a total of 20 oral prophylaxis participants from both sexes who registered to Saveetha Dental College and Hospitals, Chennai. Patients were split into two groups, with pomegranate mouthwash in group 1 and 0.2% chlorhexidine gluconate mouthwash in group 2. Oral prophylaxis was performed once the participants were enrolled as part of the analysis. After that, unstimulated saliva samples were obtained and the same for the entire bacterial colony count was cultivated in nutrient agar. The same thing repeated itself after two weeks.

Results: Within the limits of the current analysis, a decrease in the total number of colonies was observed when pomegranate mouthwash was used from 150.54 colony forming units (CFU) to 48.99 CFU compared to chlorhexidine mouthwash from 152.06 CFU to 57.7 CFU. As compared to group 2, the decline in colony count was greater in group 1.

Conclusion: The present study showed that mouthwash with pomegranate showed greater antimicrobial activity than mouthwash with chlorhexidine. After long-term clinical trials, the prospective use of pomegranate as a convenient alternative to antimicrobial drugs should be considered.

Please see the link :- https://www.ikprress.org/index.php/PCBMB/article/view/5293