Wednesday, December 16, 2020

ANTIBACTERIAL & ANTI INFLAMMATORY EFFECT OF Cassia auriculata MOUTHWASH VERSUS CHLORHEXIDINE IN PLAQUE INDUCED GINGIVITIS - A PROSPECTIVE CLINICAL & MICROBIOLOGICAL STUDY | PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

 Aim: The purpose of this study was to evaluate, through clinical and microbiological examination, the antibacterial and anti-inflammatory effect of Cassia auriculata mouthwash in Plaque induced gingivitis and to compare it with Chlorhexidine mouthwash.


Materials and Methods: With the coin toss process, thirty patients who participated in the study were randomly divided into two groups. Either herbal mouthwash or chlorhexidine was administered in each community containing 15 patients. Subgingival plaque samples were obtained at baseline and 15 days later, respectively. At baseline, and 15 days later, the Silness and Loe plaque index and Loe and Silness gingival index were reported. Patients have been asked to report any pain, changes in taste, or other side effects.

Results: The results showed that there was no statistically significant difference between group A and group B for PI and GI during the baseline period. Group B (Chlorhexidine mouthwash - control group) was substantially successful in reducing the plaque index and gingival index relative to group A after 15 days of intervention (Cassia auriculata mouthwash). The mean CFUs of group B were lower than the mean CFUs of group A at baseline and after 15 days, with a statistically significant p value of 0.001. Within group A and group B, both Cassia auriculata mouthwash and Chlorhexidine mouthwash are equally potent in significantly reducing the PI scores, GI scores, CFUs, when all these parameters were compared between baseline and day 15.

Conclusion: Cassia auriculata mouthwash among patients with plaque caused gingivitis is effective in reducing plaque, gingival inflammation and CFUs, but is not equal to that of Chlorhexidine mouthwash. However, compliance with the herbal mouthwash was safer for the patient, as the patient reported no side effects compared to chlorhexidine.

Please see the link :- https://www.ikprress.org/index.php/PCBMB/article/view/5292

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